PHOENIX and F-PHOENIX DBM® blend

Use of femoral head neck or long bone to obtain cortical bone rich in BMP osteoinductive proteins.

Viral, bacterial and fungal inactivation with successive baths of ethanol, chloroform, then hydrogen peroxide H₂O₂ (hydrogen peroxide) and finally hydrochloric acid HCl (concentration of 0.6 mol for 24 h). This last bath demineralizes the cortical bone, releasing hydroxyapatite crystals as well as BMP growth factors and obtaining demineralized bone fibers that contain less than 5% calcium.

Translucent, sticky fibers after rehydration.

In order to dehydrate bone tissue in depth in a reproducible way, guaranteeing long-term preservation of bone tissue characteristics at room temperature.

Combination of 70% PHOENIX® mineralized bone powder or chips and 30% F-PHOENIX DBM® demineralized bone fiber.

This process, with its narrow sterilization range (maximum 32 kGy), preserves the biological and structural quality of bone and DBM, while enabling effective sterilization to ISO11137 standards.

Shelf life of 5 years at room temperature. Throughout the F-PHOENIX DBM ® process, several control steps are carried out to ensure that each PHOENIX® graft meets TBF requirements before release.

During the process, each graft is subjected to rigorous controls in line with TBF standards, including a systematic functional test for Alkaline Phosphatase (PAL), an enzyme produced by differentiated osteoblasts in contact with DBM. This assay confirms the osteoinductive effect of the mixtures.